Volume 2, Issue 4, December 2019, Page: 44-50
Review on DNA Micro Array Technologyand Its Application
Takale Worku, Department of Veterinary Laboratory, Ambo University, Ambo, Ethiopia
Demessa Negassu, Department of Veterinary Laboratory, Ambo University, Ambo, Ethiopia
Received: Sep. 9, 2019;       Accepted: Oct. 16, 2019;       Published: Jan. 6, 2020
DOI: 10.11648/j.ajz.20190204.11      View  329      Downloads  92
DNA microarrays are technology that measure the expression level of thousands of genes at the same time. They need become avital tool for a good kind of biological experiments. one among the most common goals of polymer microarray experiments is to spot genes related to biological processes of interest. DNA Microarray is one such technology that allows the researchers to analyze and address problems that were once thought to be non traceable. This technology has scepter the scientific community to manage the elemental aspects underlining the expansion and development of life, additionally on explore the genetic causes of anomalies occurring within the functioning of organisms. Microarrays area unit vital as a result of they possess a large variety of genes and additionally owingto their transportable size. An important implication of the fundamental dogma of molecular biology is that there should be a strong association between the presence of a given protein in a cell and the presence of the mRNA sequence that is transcribed to build that protein. If a protein is active in a given cell, there should be a large number of copies of the mRNA sequence corresponding to that protein. Conversely, if a protein is not active in a cell, there should be few copies of the corresponding mRNA sequence. Thus, DNA microarrays attempt to evaluate the presence or absence of proteins in a cell and their relative abundance by measuring the relative abundance of the corresponding mRNA sequences. This review addresses the potential uses of DNA microarray technology, principle of the technology, its application and limitation of the technology.
DNA Microarray, Protein Microarray, Hybridization, cDNA
To cite this article
Takale Worku, Demessa Negassu, Review on DNA Micro Array Technologyand Its Application, American Journal of Zoology. Vol. 2, No. 4, 2019, pp. 44-50. doi: 10.11648/j.ajz.20190204.11
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